The White House recently launched a women’s health initiative aimed at delaying menopause and its associated health risks. This initiative stems from growing research suggesting that the ovaries, far beyond their role in reproduction, are central to a woman’s overall health. Jessica Reyes discusses the initiative with Dr. Jude Black.
The “Control Center” of Aging
Scientists believe that the ovaries act as a control center, communicating with and influencing other organs through hormones and chemicals. When ovarian function declines, as it does during menopause, the risk of various health problems increases, including dementia, cardiovascular disease, and osteoporosis. This decline also appears to correlate with shorter lifespans, especially in women who experience early menopause.
The race to extend ovarian function
Researchers are now exploring ways to prolong ovarian function and delay menopause. One company is testing a pharmaceutical version of AMH, a hormone that regulates egg maturation, to reduce egg loss and preserve ovarian reserves. A clinical trial at Columbia University is investigating the use of rapamycin, an immunosuppressive drug, to slow egg loss and potentially extend ovarian function.
Learning as we go
While the exact connection between ovarian function and overall health remains unclear, studies in animals suggest that prolonging ovarian function can improve health and increase longevity. Scientists hope that understanding the mechanisms behind premature ovarian aging will provide valuable insights into aging in general, benefiting both women and men.
To learn more about Dr. Jude Black visit her website and connect with her on Instagram.
